2022-12-09 作者：Yingzi Gene
China is a major producer of agriculture and animal husbandry, with the production of livestock and poultry meat accounting for approximately 29% of the global total, and ranking first in the world in terms of pig production and egg output, and second in broiler chicken production. Additionally, China is also a major player in global seafood import and export trade, with the seafood production consistently ranking first worldwide for 28 consecutive years since 1989.
As the starting point of the industry, animal breeding determines the quality and efficiency of the entire industry chain. China is currently in the stage of provenance technology breakthrough, and molecular breeding technologies can help breeding companies accelerate the animal breeding cycle and provide new impetus to the industry. Genomic breeding, in particular, has significantly advanced the efficiency of biological breeding. Genomic breeding is essentially a "scientific fortune-telling" method, where high-density molecular genetic markers spanning the entire genome are used, along with statistical approaches, to assess the genetic quality of the next generation. The use of genomic breeding technologies can fundamentally enhance the efficiency and precision of breeding selection, allowing for the rapid development of new animal and plant varieties/strains that adapt to natural climates and meet market demands.
On December 8, 2022, the online seminar on the Cutting-edge Animal Genomic Breeding and Industrial Applications, jointly sponsored by Yingzi Gene, MGI and Yeasen and organized by the Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education at Huazhong Agricultural University, Shenzhen National Gene Bank, the National Livestock Science and Technology Innovation Alliance, and the Frontiers in Genomic Breeding, was held successfully. The conference gathered eight experts from the animal breeding industry to discuss cutting-edge breeding technologies, including functional genomics research, genome-wide selection, gene editing, and their applications in the animal industry. Professor Li Xinyun, the doctoral supervisor at Huazhong Agricultural University and Chief Scientist of Wuhan Yingzi Gene preside over the first half of the conference and explained the purpose of this seminar, and Dr. Zheng Zhuqing, the expert from Wuhan Yingzi Gene and post-doctoral of Huazhong Agricultural University, chaired the second half of the conference.
The seminar began with a presentation by Dr. Wang Yanfang, a researcher from the Institute of Animal Science and Veterinary Medicine of Chinese Academy of Agricultural Sciences on "Cold Stress-mediated Reprogramming of Porcine Fat". She discussed the current status of modern domestic pigs and the economic impact of fat in the production efficiency of pigs, described the importance of porcine fat traits in quality improvement and their role in cold stress and revealed the cold resistance mechanism in pigs, providing insights for quality enhancement and industry applications.
Professor Xu Peng from Xiamen University delivered a presentation on "Research on Genomic Selection and Breeding in Disease Resistance of Chinese Yellow Croaker". He discussed the current status of Chinese yellow croaker aquaculture industry and highlighted the significant challenges it faces in terms of industry health and sustainable development, and also explained how genomic selection technologies are being used to breed Chinese yellow croaker strains and successfully apply liquid chip technology to disease resistance breeding practices in aquatic animals.
Professor Nie Qinghua from South China Agricultural University explained in his presentation on "Innovation and Industry Applications in Yellow Feather Broiler Breeding", the current status and industrial challenges in the development of yellow feather broilers, also introduced the latest research achievements and the application of molecular breeding technologies in yellow feather broiler breeding, and finally showcased the industrial achievements of yellow feather broilers to date and discussed the new opportunities and challenges facing this industry.
Professor Jiang Yu from Northwest Agriculture & Forestry University delivered a report on " Breeding in Cattle and Sheep From Genomic Selection to Molecular Design". He discussed his insights into breeding of ruminant livestock, the application of low-depth resequencing technology in genomic selection for dairy cattle, and the design approach for molecular breeding, and also presented the process of selecting excellent genes in genomic selection and molecular breeding for dairy cattle and sheep, along with their industrial applications.
Professor Miao Yiliang from Huazhong Agricultural University presented a speech on "Innovation in Pig Somatic Cell Reprogramming and Cloning Technology", discussing the challenges in pig breeding. He focused on the mechanism of porcine oocyte maturation and how granulosa cell autophagy affects the development of porcine oocyte, talked about the obstacles related to histone methylation reprogramming during the development of pig cloned embryos, and proposed innovative techniques to enhance the development rate of pig cloned embryos by optimizing the porcine oocyte maturation system and eliminating somatic cell reprogramming barriers.
Professor Sun Dongxiao from China Agricultural University provided a comprehensive overview of the domestic and international genomic genetic assessment systems for dairy cattle in his presentation on "Advancements and Trends in Genomic Selection Research and Applications for Dairy Cattle". He emphasized the revolutionary impact of genomic selection technology on dairy cattle breeding and offered insights into the future of genomic selection breeding for dairy cattle in China.
The final speaker was Dr. Ding Rongrong, a postdoctoral researcher from the Research Group of Professor Wu Zhenfang at South China Agricultural University. In her presentation on "Construction and Application of a Large Swine Genome Filling Database", Dr. Ding introduced the technical methods for genetic analysis of economic traits in pigs, discussed the challenges currently faced by various gene chips and presented the construction approach of a large swine genome filling database, along with its applications in breeding.
At the end of the seminar, Professor Li Xinyun from Huazhong Agricultural University provided a concise summary of the in-depth presentations by the experts and professors and expressed his gratitude to them.
This seminar has received extensive attention from experts and scholars in the field of animal genetic breeding. The event was live-streamed on six platforms simultaneously, with a total of 12,000 viewers. Participants, including faculty and students, actively engaged in questioning and exchanging ideas, all expressing that they greatly benefited from this academic seminar. The publicly available portions of the presentations have been archived and can be accessed by interested teachers and students through scanning the QR code below. Additionally, you can add the customer personnel WeChat (QR code at the end of the document) to join the Genetic Breeding Discussion Group, so as to receive real-time updates on the latest research developments and academic exchange activities in the field of genetic breeding.
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