In recent years, the regulation of RNA modification-mediated gene expression has become one of the hotspots in the field of epigenetic research, with m6A RNA modification being one of the mainstream research directions. I happened to come across an article about single cell m6A sequencing recently published in Molecular Cell by Kate Meyer's research group at Duke University, titled "scDART-seq Reveals Distinct m6A Signatures and mRNA Methylation Heterogeneity in Single Cells"
2022-04-12
The paper is "Cell Type-specific 3D Epigenomes in the Developing Human Cortex", published in Nature on October 14, 2020. In this article, multi-omics approaches are utilized comprehensively to analyze key genetic variations discovered through GWAS, eQTL or selective sweep, making it an invaluable analytical template. It holds great reference value.
This paper has analyzed and integrated epigenomic data from published studies on pig muscle and fat tissues, and identified functional cis-regulatory elements for miRNAs, which has provides a theoretical basis for understanding the molecular mechanisms of miRNA regulation in pig muscle and fat. Yingzi Genes provided resource support for the epigenomic analysis in this study.
2022-03-24
Yingzi Gene providing genetic breeding experts with a complete solution for the design (including data accumulation), preparation, detection and breeding applications of functional locus gene chips.