The core algorithm products are fully self-developed without relying on any third-party software package, and not subject to any breeding computation patents both at home and abroad. Composed of genomic selection and breeding calculation, it is the only software currently available for genomic breeding calculation and suitable for genetic research in both animals and plants. Through algorithm innovation, parallel computation, and hardware acceleration strategies, improvements in computation efficiency have been achieved significantly. The larger the number of genotyping individuals is, the higher the computation efficiency will be. It can efficiently handle millions of populations and tens of millions of molecular marker breeding big data. Compared with similar international software, for the same data volume, HiBLUP breeding value assessment offers higher accuracy and lower computation costs.